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Publications

Chem Catalysis, 2024, 101184

Visible light-driven excited-state copper-BINAP catalysis for accessing diverse chemical reactions

Upasana Mukherjee, Jagrut A. Shah, Ming-Yu Ngai

J. Am. Chem. Soc. 2024, 31391–31399

Cobalt-Hydride-Catalyzed Alkene-Carboxylate Transposition (ACT) of Allyl Carboxylates

Gaoyuan Zhao, Arman Khosravi, Sahil Sharma, Djamaladdin G. Musaev, and Ming-Yu Ngai*

J. Am. Chem. Soc. 2024, 21271–21279

Harnessing Bromo/Acyloxy Transposition (BrAcT) and Excited-State Copper Catalysis for Styrene Difunctionalization

Mukherjee, U.; Shah, J.A..; Musaev, DG.; Ngai, M.-Y.*,

Chem. 2024, 10, 686.

Merging Excited-State Copper Catalysis and Triplet Nitro(hetero)arenes for Direct Synthesis of 2-Aminophenol Derivatives

Shah, J.A..; Banerjee, A.; Mukherjee, U.; Ngai, M.-Y.*,

J. Am. Chem. Soc. 2023, 145, 8275.

Expanding Reaction Profile of Allyl Carboxylates via 1,2-Radical Migration (RaM): Visible-Light-Induced Phosphine-Catalyzed 1,3-Carbobromination of Allyl Carboxylates

Zhao, G.; Lim S.; Musaev, D. G.; Ngai, M.-Y.*,

ChemCatChem., 2023, 15, e202201128.

Synthesis of Ketonylated Carbocycles via Excited-State Copper-Catalyzed Radical Carbo-Aroylation of Unactivated Alkenes

Sarkar, S.; Banerjee, A.; Ngai, M.-Y.*,

CCS Chem., 2023, 5, 106.

Excited-State Palladium-Catalyzed ?-Selective C1-Ketonylation

Zhao, G.;# Mukherjee, U.# Zhou, L.; Mauro, J. N.; Wu, Y.; Liu, P.; Ngai, M.-Y.,

Handbook of CH-Functionalization, 2022

Book Chapter: (Hetero)aryl C-H Amination via Organic Electrochemistry

Shah, J. A.; Ngai, M.-Y.*

J. Am. Chem. Soc., 2022, 144, 20884.

Excited-State Copper-Catalyzed [4+1] Annulation Reaction Enables Modular Synthesis of ?,?-Unsaturated-?-Lactams

Sarkar, S.; Banerjee, A.; Shah, J.; Mukherjee, U.; Frederiks, N. C.; Johnson, C. J.; Ngai, M.-Y.,

Highlighted in Org. Chem. Abstracts, 2023.

Chem. Sci., 2022, 13, 6276.

C2-Ketonylation of Carbohydrates via Excited-State Palladium-Catalyzed 1,2-Spin-Center Shift

Zhao, G.; Mukherjee, U.; Zhou, L.; Wu, Y.; Yao, W.; Mauro, J. N.; Liu, P.; Ngai, M.-Y.,

J. Am. Chem. Soc. 2022, 144, 3353.

Excited-State Palladium-Catalyzed Radical Migratory Mizoroki-Heck Reaction Enables C2-Alkenylation of Carbohydrates

Yao, W.; # Zhao, G.;# Zhou, L.; Wu, Y.; Mukherjee, U.; Liu, P.; Ngai, M.-Y.,

Highlighted in ACS Cent. Sci. 2023, 9, 2175

Angew. Chem. Int. Ed. 2022, 61, e202113841.

Excited-State Copper Catalysis for the Synthesis of Heteroarenes

Banerjee, A.; Sarkar, S.; Shah, J. A.; Frederiks, N. C.; Bazan Bergamino, E. A.; Johnson, C. J.; Ngai, M.-Y.*

ChemCatChem, 2022, 14, e202101292.

Asymmetric Photocatalysis Enabled by Chiral Organocatalysts

Yao, W.; Bazan-Bergamino, E. A.; Ngai, M.-Y.*

J. Am. Chem. Soc. 2021, 143, 8590.

Nickel-Catalyzed Radical Migratory Coupling Enables C-2 Arylation of Carbohydrates

Zhao, G.; Yao, W.; Kevlishvili, I.; Mauro, J. N.; Liu, P.; Ngai, M.-Y.

Highlighted in Org. Chem. Highlights, 2022.

Highlighted in Chem-Station, 2022.

J. Am. Chem. Soc. 2021, 143, 1728.

Excited-State Palladium-Catalyzed 1,2-Spin-Center Shift Enabled Selective C-2 Reduction, Deuteration, and Iodination of Carbohydrates

Zhao, G.#; Yao, W.#; Mauro, J. N.; Ngai, M.-Y.*

Highlighted in Org. Chem. Highlights, 2022.

Angew. Chem. Int. Ed. 2020, 59, 21475.

Redox-Neutral TEMPO Catalysis Toward Direct Radical (Hetero)Aryl C-H Di- and Trifluoromethoxylation

Lee, J. W.#; Lim, S.#; Maienshein, D. N.; Liu, P.; Ngai, M.-Y.

Highlighted in Synfacts, 2020, 16, 1342.

Emerging Fluorinated Motifs, Properties, Synthesis and Applications 2020, pp 225-249, ISBN: 9783527346813.

Book Chapter: Direct Trifluoromethoxylation of Aromatics and Heteroaromatics

Lee, J. W.; Lee, K. N.; Ngai, M.-Y.*

ACS Catal. 2019, 9, 10358.

Photocatalytic Aroyl-(Hetero)arylation of Unactivated Alkenes: Pathway to 1,4-, 1,6- and 1,7-Diketones

Sarkar, S.#; Banerjee, A.#; Yao, W.; Patterson, E. V.; Ngai, M.-Y.*

Angew. Chem. Int. Ed. 2019, 58,

β-Selective Aroylation of Alkenes by Photoredox Catalysis

Lei, Z.#; Banerjee, A.#; Kusevska, E.; Rizzo, E. R.; Liu, P.; Ngai, M.-Y.

Angew. Chem. Int. Ed. 2019, 58, 11171.

Synthesis of Tri- and Difluoromethoxylation Compounds via Visible Light Photoredox Catalysis

Lee, J. W.; Lee, K. N.; Ngai, M.-Y.*

Chem. Sci. 2019, 10, 3217.

Catalytic Difluoromethoxylation of Arenes and Heteroarenes

Lee, J. W.#; Zheng, W.#; Morales-Rivera, C. A.; Liu, P.; Ngai, M.-Y.

Highlighted in ChemistryView, 2019.

Highlighted in Synfacts, 2019, 15, 0520.

Highlighted in Chem. Sci. Editors Choice Collection, 2019.

Synthesis 2019, 51, 303. (Invited Review by Professor Dieter Enders)

Acyl Radical Chemistry via Photoredox Catalysis

Banerjee, A.#; Lei, Z.#; Ngai, M.-Y.*

Tetrahedron 2018, 74, 7127. (Invited Review for Organo Fluorine Chemistry Special Issue)

Recent Development of Catalytic Trifluoromethoxylation Reactions

Lee, K. N.; Lee, J. W.; Ngai, M.-Y.*

Angew. Chem. Int. Ed. 2018, 57, 13795.

Redox-active Reagents for Photocatalytic Generation of the OCF3 Radical and (Hetero)aryl C-H Trifluoromethoxylation

Zheng, W.; Lee, J. W.; Morales-Rivera, C. A.; Liu, P.; Ngai, M.-Y.

Chem. Comm. 2018, 54, 6935 (Invited Article, Emerging Investigator Issue 2018)

Transition-Metal-Free C-H Amidation and Chlorination: Synthesis of N/N'-Mono-Substituted Imidazopyridin-2-ones

Lee, K. N.; Spiegowski, D. N.; Lee, J. W.; Lim, S.; Zhao, F.; Ngai, M.-Y.*,

Angew. Chem. Int. Ed. 2018, 57, 9645.

Catalytic C-H Trifluoromethoxylation of Arenes and Heteroarenes

Zheng, W.; Morales-Rivera C. A.; Lee, J. W.; Liu, P.; Ngai, M.-Y.

Highlighted in Angew. Chem. Int. Ed. 2018, 57, 7942.

Chem. Commun. 2017, 53, 13093.

Recent Developments in Transition-Metal Photoredox-Catalysed Reactions of Carbonyl Derivatives

Lee, K. N.; Ngai, M.-Y.*

Chem. Sci. 2017, 8, 6066.

Selective C-O Bond Formation via Photocatalytic Radical Coupling Strategy: Access to Perfluoroalkoxylated (ORF) Arenes and Heteroarenes

Lee, J. W.; Spiegowski, D. N.; Ngai, M.-Y.*,

Highlighted in Synfacts, 2017, 13, 1142.

J. Am. Chem. Soc., 2017, 139, 5003.

β-Selective Reductive Coupling of Alkenylpyridines with Al-dehydes and Imines via Synergistic Lewis Acid/Photoredox Catalysis

Lee, K. N.#; Lei, Z.#; Ngai, M.-Y.*

ACS Med. Chem. Lett., 2017, 8, 287.

Development of [18F]Maleimide-Based Glycogen Synthase Kinase-3β Ligands for Positron Emission Tomography Imaging

Kongzhen Hu, K.; Patnaik, D.; Collier, T. L.; Lee, K. N.; Gao, H.; Swoyer, M. R.; Rotstein, B. H.; Krishnan, H. S.; Liang, S. H.; Wang, J.; Yan, Z.; Hooker, J. M.; Vasdev, N.; Haggarty, S. J.; Ngai, M.-Y.*

Org. Biomol. Chem. 2016, 14, 5599 (Invited article, New Talent Themed Issue).

Mechanistic Studies on Intramolecular C-H Trifluoromethoxylation of (Hetero)arenes via OCF3-Migration

Lee, K. N.; Lei, Zhen; Morales-Rivera C.A.; Liu, P.; Ngai, M.-Y.*

Synlett, 2016, 27, 313. (Invited Synpact Review).

Synthesis of Trifluoromethoxylation of (Hetero)arenes via OCF3-Migration.

Lee, K. N.; Lee, J. W.; Ngai, M.-Y.*

Chem. Sci. 2016, 7, 424.

Access to a New Class of Synthetic Building Blocks via Trifluoromethoxylation of Pyridines and Pyrimidines.

Feng, P.#; Lee, K. N.#; Lee, J. W.; Zhan, C, Ngai, M.-Y.*

Top 50 Articles of 2016: Organic Chemistry (50 most downloaded Chemical Science articles of 2016).

Highlighted in Org. Process Res. Dev., 2015, 19, 1918.

J. Vis. Exp., 2016, 107, e53789. (Invited article)

Protocol for the Synthesis of ortho-Trifluoromethoxylated Aniline Derivatives.

Feng, P; Ngai, M.-Y.*

J. Am. Chem. Soc. 2015, 137, 11594.

A Highly Convergent Total Synthesis of Leustroducsin B.

Trost, B. M.; Biannic, B.; Brindle, C. S.; O'Keefe, B. M.; Hunter, T. J.; Ngai, M.-Y.

Angew. Chem. Int. Ed. 2014, 53, 14559.

Trifluoromethoxylation of Arenes: Synthesis of Ortho-Trifluoromethoxylated Aniline Derivatives by OCF3-Migration

Hojczyk, K. N.; Feng, P; Zhan, C, Ngai, M.-Y.*

J. Am. Chem. Soc. 2013, 135, 13278.

Pd-Catalyzed Aryl C-H Imidation with Arene as the Limiting Reagent

Boursalian, G. B.#; Ngai, M.-Y.#; Hojczyk, K. N.; Ritter, T.

Org. Lett. 2011, 13, 1900.

Ligand Accelerated Enantioselective Propargylation of Aldehydes via Allenylzinc Reagents

Trost, B. M.; Ngai, M.-Y.; Dong, G.-B.

J. Am. Chem. Soc. 2008, 130, 14891.

Enantioselective Iridium Catalyzed Carbonyl Allylation From the Alcohol or Aldehyde Oxidation Level via Transfer Hydrogenative Coupling of Allyl Acetate

Kim, I.-S.; Ngai, M.-Y.; Krische, M. J.

Org. Lett. 2008, 10, 2705.

Ruthenium Catalyzed C-C Bond Forming Transfer Hydrogenation: Reductive Coupling of Allenes to Paraformaldehyde and Higher Aldehydes

Ngai, M.-Y.; Skucas, E.; Krische, M. J.

J. Am. Chem. Soc. 2008, 130, 6340.

Enantioselective C-H Allylation of Alcohols Employing Allyl Acetate: Iridium Catalyzed Carbonyl Allylation from the Alcohol Oxidation Level

Kim, I.-S.; Ngai, M.-Y.; Krische, M. J.

J. Am. Chem. Soc. 2007, 129, 12644.

Enantioselective Iridium Catalyzed Imine Vinylation: Optically Enriched Allylic Amines via Alkyne-Imine Reductive Coupling Mediated by Hydrogen,

Ngai, M.-Y.; Barchuk, A.; Krische, M. J.

Acc. Chem. Res. 2007, 40, 1394.

Enantiomerically Enriched Allylic Alcohols and Allylic Amines via C-C Bond Forming Hydrogenation: Asymmetric Carbonyl and Imine Vinylation

Skucas, E.; Ngai, M.-Y.; Komanduri V.; Krische, M. J.

J. Am. Chem. Soc. 2007, 129, 8432.

Allylic Amines via Iridium Catalyzed C-C Bond Forming Hydrogenation: Imine Vinlyation in the Absence of Stoichiometric Byproducts or Metallic Reagents

Barchuk, A.; Ngai, M.-Y.; Krische, M. J.

J. Org. Chem. 2007, 72, 1063.

Hydrogen-Mediated C-C Bond Formation: A Broad New Concept in Catalytic C-C Coupling

Ngai, M.-Y.; Kong, J.-R.; Krische, M. J.

J. Am. Chem. Soc. 200

Iridium Catalyzed C-C Bond Forming Hydrogenation: Direct Regioselective Reductive Coupling of Alkyl-Substituted Alkynes to Activated Ketones

Ngai, M.-Y.; Barchuk, A.; Krische, M. J.

Lessons in Green Chemistry from the Smallest of Molecules: C-C Bond Formation via Catalytic Hydrogenation

Ngai, M.-Y.; Krische, M. J.

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